Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 3/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.51 |
| ▸ | ITGAV | P06756 | 2/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | SDCBP | O00560 | 1/20 | 0.49 |
| ▸ | SDC2 | P34741 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2014415 | 1.00 | FPR2 (0.53) | FPR2ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL5191620 | 0.87 | FPR2 (0.59) | FPR2ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL14506086 | 0.87 | ITGB3 (0.48) | FPR2ITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL14520629 | 0.85 | ITGB3 (0.52) | ITGB3ITGB1ITGAVITGA5MMP2 | |
| SCHEMBL12572489 | 0.85 | ITGB3 (0.52) | ITGB3ITGB1ITGAVITGA5MMP2 | |
| SCHEMBL8065362 | 0.84 | ALDH1A1 (0.62) | ITGB3ITGB1ITGAVITGA5MAPK1 | |
| SCHEMBL29060375 | 0.84 | ALDH1A1 (0.62) | ITGB3ITGB1ITGAVITGA5MAPK1 | |
| SCHEMBL8349459 | 0.84 | ALDH1A1 (0.62) | ITGB3ITGB1ITGAVITGA5MAPK1 | |
| SCHEMBL2443868 | 0.84 | GAA (0.51) | ITGB3ITGB1ITGAVITGA5CTSK | |
| SCHEMBL5191624 | 0.84 | GAA (0.51) | ITGB3ITGB1ITGAVITGA5CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492577-B2 | Process for preparation of valsartan intermediate | HETERO RESEARCH FOUNDATION (IN) | 2013-07-23 | — | — | US | disclosed |
| US-20110237822-A1 | PROCESS FOR PREPARATION OF VALSARTAN INTERMEDIATE | HETERO RESEARCH FOUNDATION (IN) | 2011-09-29 | — | — | US | disclosed |
| EP-2260018-A2 | PROCESS FOR PREPARATION OF VALSARTAN INTERMEDIATE | Hetero Research Foundation (IN) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009125416-A2 | PROCESS FOR PREPARATION OF VALSARTAN INTERMEDIATE | HETERO RESEARCH FOUNDATION (IN) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237822-A1 | PROCESS FOR PREPARATION OF VALSARTAN INTERMEDIATE | REN, AGT, ACE | FPR2 2326/4885ITGB3 3298/4885ITGB1 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.