Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531552 | 1.00 | RAPGEF4 (0.41) | RAPGEF4EGFRPDGFRBKDRSYK | |
| SCHEMBL24401644 | 0.77 | KCNH3 (0.39) | RAPGEF4EGFRPDGFRBKDRMAPT | |
| SCHEMBL29531859 | 0.77 | KCNH3 (0.39) | RAPGEF4EGFRPDGFRBKDRMAPT | |
| SCHEMBL29531896 | 0.76 | FGFR4 (0.48) | ALDH1A1GAA | |
| SCHEMBL24401494 | 0.74 | GRM4 (0.53) | EGFRMAPTGRM4ALDH1A1GAA | |
| SCHEMBL29532275 | 0.74 | GRM4 (0.53) | EGFRMAPTGRM4ALDH1A1GAA | |
| SCHEMBL12727110 | 0.74 | RAB9A (0.47) | EGFRMAPTTP53ALDH1A1GAA | |
| SCHEMBL13506395 | 0.74 | CYP1A2 (0.49) | EGFRMAPTALDH1A1GAARAB9A | |
| SCHEMBL16900175 | 0.72 | EGFR (0.49) | EGFRMAPTTP53SMN1; SMN2HTT | |
| SCHEMBL24401581 | 0.69 | KDM4E (0.35) | MAPTTP53ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220140258-A1 | IRIDIUM COMPLEX, NITROGEN-CONTAINING TRIDENTATE CARBENE CHELATE, AND ORGANIC LIGHT-EMITTING DIODE | NATIONAL TSING HUA UNIVERSITY (TW) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220140258-A1 | IRIDIUM COMPLEX, NITROGEN-CONTAINING TRIDENTATE CARBENE CHELATE, AND ORGANIC LIGHT-EMITTING DIODE | NR2E3, CHRM1, CBR3 | RAPGEF4 2194/4885EGFR 695/4885PDGFRB 3879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.