Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | IDH2 | P48735 | 2/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531859 | 1.00 | KCNH3 (0.39) | KCNH3TRPA1RAPGEF4EGFRPDGFRB | |
| SCHEMBL29531777 | 0.78 | TUBB4A (0.50) | KCNH3TRPA1TAS2R14GRM4IDH2 | |
| SCHEMBL24401492 | 0.78 | TUBB4A (0.50) | KCNH3TRPA1TAS2R14GRM4IDH2 | |
| SCHEMBL24401645 | 0.77 | RAPGEF4 (0.41) | RAPGEF4EGFRPDGFRBKDRTP53 | |
| SCHEMBL29531552 | 0.77 | RAPGEF4 (0.41) | RAPGEF4EGFRPDGFRBKDRTP53 | |
| SCHEMBL14295964 | 0.77 | KCNH3 (0.51) | KCNH3THRBLMNABRD4 | |
| SCHEMBL24401583 | 0.74 | NR4A2 (0.36) | KCNH3MAPTHTTLMNABRD4 | |
| SCHEMBL29531855 | 0.74 | NR4A2 (0.36) | KCNH3MAPTHTTLMNABRD4 | |
| SCHEMBL29531896 | 0.72 | FGFR4 (0.48) | BRD4 | |
| SCHEMBL13483717 | 0.68 | KIF11 (0.43) | KCNH3RAPGEF4MAPTTAS2R14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220140258-A1 | IRIDIUM COMPLEX, NITROGEN-CONTAINING TRIDENTATE CARBENE CHELATE, AND ORGANIC LIGHT-EMITTING DIODE | NATIONAL TSING HUA UNIVERSITY (TW) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220140258-A1 | IRIDIUM COMPLEX, NITROGEN-CONTAINING TRIDENTATE CARBENE CHELATE, AND ORGANIC LIGHT-EMITTING DIODE | NR2E3, CHRM1, CBR3 | KCNH3 1596/4885TRPA1 1511/4885RAPGEF4 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.