Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405507 | 0.83 | PDE10A (0.37) | GSK3BPDE10AMAP4K1PGRPRKDC | |
| SCHEMBL24405354 | 0.82 | GSK3B (0.40) | GSK3BPDE10AMAP4K1PGRPRKDC | |
| SCHEMBL24405741 | 0.77 | GLO1 (0.41) | GSK3BPDE10AMAP4K1PGR | |
| SCHEMBL24405829 | 0.76 | PDE10A (0.40) | GSK3BPDE10AMAP4K1PGRKDM4E | |
| SCHEMBL24405558 | 0.75 | PGR (0.43) | GSK3BPDE10AMAP4K1PGRPRKDC | |
| SCHEMBL24405371 | 0.72 | PGR (0.36) | GSK3BPDE10AMAP4K1PGRPRKDC | |
| SCHEMBL24405590 | 0.72 | GRM5 (0.48) | GSK3BPDE10AMAP4K1PGRPRKDC | |
| SCHEMBL24405506 | 0.71 | PRKDC (0.39) | GSK3BMAP4K1PGRPRKDCKDM4E | |
| SCHEMBL24405475 | 0.71 | CRHR1 (0.37) | GSK3BPDE10AMAP4K1PGRPRKDC | |
| SCHEMBL6362809 | 0.69 | PGR (0.68) | GSK3BPGRKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |