Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405984 | 0.82 | EED (0.45) | PGRPARGEEDMAP4K1PIK3CA | |
| SCHEMBL1269228 | 0.72 | PGR (0.41) | PGRPARGMAP4K1PIK3CAPRKDC | |
| SCHEMBL1269624 | 0.70 | PGR (0.34) | PGRMAP4K1GRM4 | |
| SCHEMBL1269274 | 0.68 | XBP1 (0.31) | PGRMAP4K1 | |
| SCHEMBL24405802 | 0.67 | PGR (0.40) | PGRPARGPIK3CAPRKDCGRM4 | |
| SCHEMBL24405904 | 0.67 | LRRK2 (0.55) | MAP4K1PIK3CA | |
| SCHEMBL6362809 | 0.64 | PGR (0.68) | PGRPARGADORA3 | |
| SCHEMBL21474185 | 0.64 | ROCK2 (0.39) | PIK3CAPDE10A | |
| SCHEMBL24405371 | 0.64 | PGR (0.36) | PGRPARGMAP4K1PIK3CAPRKDC | |
| SCHEMBL24405899 | 0.62 | PGR (0.37) | PGRPARGPIK3CAPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |