Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405700 | 0.78 | NPEPPS (0.42) | PGRPIK3CDPIK3CAMTORPIK3CG | |
| SCHEMBL24405682 | 0.75 | PGR (0.36) | PGRMAP4K1AGERPIK3CDPIK3CA | |
| SCHEMBL24405534 | 0.73 | PGR (0.38) | PGRMAP4K1AGERPIK3CDPIK3CA | |
| SCHEMBL27331946 | 0.73 | PGR (0.40) | PGRMAP4K1AGERPIK3CDPIK3CA | |
| SCHEMBL24405718 | 0.73 | PIK3CD (0.36) | PGRPIK3CDPIK3CAMTORPIK3CG | |
| SCHEMBL24405558 | 0.71 | PGR (0.43) | PGRMAP4K1PIK3CDPIK3CAMTOR | |
| SCHEMBL24405520 | 0.71 | PIK3CA (0.36) | PGRMAP4K1PIK3CDPIK3CAMTOR | |
| SCHEMBL27261699 | 0.69 | HCAR3 (0.46) | PGRMAP4K1PIK3CAMTORGSK3B | |
| SCHEMBL24405723 | 0.69 | GAA (0.39) | PGRGAAGSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL24405387 | 0.68 | HCAR3 (0.43) | PGRPIK3CDPIK3CAMTORPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |