Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405700 | 0.83 | NPEPPS (0.42) | PGRGSK3BTSHRMEN1KMT2A | |
| SCHEMBL24405718 | 0.82 | PIK3CD (0.36) | PGRGSK3BTSHRMEN1KMT2A | |
| SCHEMBL21474179 | 0.81 | GAA (0.39) | PGRTRPC5GSK3BTSHRMEN1 | |
| SCHEMBL21474157 | 0.77 | POLB (0.41) | PGRGSK3BTSHRMEN1KMT2A | |
| SCHEMBL24405558 | 0.76 | PGR (0.43) | PGRGSK3BMEN1KMT2ACYP1A2 | |
| SCHEMBL24405891 | 0.75 | PGR (0.33) | PGRGSK3BCYP1A2MAP4K1AGER | |
| SCHEMBL24405387 | 0.75 | HCAR3 (0.43) | PGRGSK3BCYP1A2NPEPPSPIK3CD | |
| SCHEMBL24405534 | 0.73 | PGR (0.38) | PGRGSK3BCYP1A2MAP4K1AGER | |
| SCHEMBL24405723 | 0.73 | GAA (0.39) | PGRGSK3BTSHRMEN1KMT2A | |
| SCHEMBL23119712 | 0.72 | GAA (0.40) | PGRGSK3BTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |