SCHEMBL2440720

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17541809	0.89	TSHR (0.46)	CYP1A2CYP2C19ALDH1A1CNR1TSHR
	SCHEMBL11560785	0.88	CYP1A2 (0.44)	CYP1A2CYP2C9CYP2C19TAAR1MEN1
	SCHEMBL19396004	0.78	CA2 (0.48)	ALDH1A1L3MBTL1TSHR
	SCHEMBL188308	0.78	TSHR (0.64)	CYP2C19ALDH1A1IDO1TSHR
	SCHEMBL2441925	0.78	ACHE (0.46)	CYP1A2TAAR1MEN1ALDH1A1KMT2A
	SCHEMBL4543334	0.78	ESR1 (0.54)	CYP2C19TAAR1ALDH1A1KMT2AL3MBTL1
	SCHEMBL10618120	0.78	ALDH1A1 (0.40)	CYP1A2CYP2C9CYP2C19MEN1ALDH1A1
	SCHEMBL4087046	0.78	GFER (0.54)	MEN1ALDH1A1KMT2AMAPTMAOB
	SCHEMBL19396020	0.78	TAAR1 (0.46)	TAAR1MEN1ALDH1A1KMT2AMAPT
	SCHEMBL12708608	0.78	TSHR (0.48)	CYP1A2CYP2C19ALDH1A1MAPTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.