SCHEMBL4087046

SCHEMBL4087046

Nc1ccc(CC[N+](=O)[O-])cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.54
RECQL P46063 1/20 0.48
MAOB P27338 4/20 0.46
MAOA P21397 2/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.42
CYP3A4 P08684 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LOXL2 Q9Y4K0 2/20 0.41
CYP19A1 P11511 1/20 0.41
KCNJ1 P48048 1/20 0.39
KCNH2 Q12809 1/20 0.39
CA9 Q16790 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA14 Q9ULX7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17541809 0.89 TSHR (0.46) ALDH1A1TSHRCYP3A4TDP1LOXL2
SCHEMBL188308 0.78 TSHR (0.64) ALDH1A1TSHRLOXL2KCNJ1KCNH2
SCHEMBL19396004 0.78 CA2 (0.48) ALDH1A1TSHRKCNJ1KCNH2CA2
SCHEMBL509535 0.78 TAAR1 (0.46) ALDH1A1TSHRCYP19A1KCNJ1KCNH2
SCHEMBL2441925 0.78 ACHE (0.46) ALDH1A1TSHRTDP1KCNJ1KCNH2
SCHEMBL19396020 0.78 TAAR1 (0.46) ALDH1A1TSHRTDP1KCNJ1KCNH2
SCHEMBL4543334 0.78 ESR1 (0.54) ALDH1A1TSHRCYP3A4TDP1CA2
SCHEMBL2440720 0.78 CYP1A2 (0.47) MAOBALDH1A1TSHRMEN1MAPT
SCHEMBL12708608 0.78 TSHR (0.48) ALDH1A1TSHRCYP3A4TDP1LOXL2
SCHEMBL9810055 0.78 KCNJ1 (0.53) MAOBALDH1A1TSHRLOXL2KCNJ1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086060-B1 HYDRAZINIUM NITROFORMATE BASED HIGH PERFORMANCE SOLID PROPELLANTS NL ORGANISATIE VOORTOEGEPAST N (NL) 2004-11-10 EP claimed
EP-1086060-A1 HYDRAZINIUM NITROFORMATE BASED HIGH PERFORMANCE SOLID PROPELLANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2001-03-28 EP claimed
WO-1999059940-A1 HYDRAZINIUM NITROFORMATE BASED HIGH PERFORMANCE SOLID PROPELLANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPIJK ONDERZOEK TNO (NL) 1999-11-25 WO claimed
US-12617738-B2 Removing dissolved gasses from propellant compositions GOODRICH CORPORATION (US) 2026-05-05 US disclosed
US-20230250038-A1 REMOVING DISSOLVED GASSES FROM PROPELLANT COMPOSITIONS GOODRICH CORPORATION 2023-08-10 US disclosed
EP-3137440-B1 BONDING AGENTS FOR NITROGEN-CONTAINING OXIDIZERS RAYTHEON CO (US) 2021-01-20 EP disclosed
EP-3230235-B1 FERROCENYL BONDING AGENT OXIDIZERS RAYTHEON CO (US) 2019-08-21 EP disclosed
US-10227267-B2 Bonding agents for nitrogen-containing oxidizers RAYTHEON COMPANY (US) 2019-03-12 US disclosed
US-10196324-B2 Ferrocenyl bonding agent oxidizers RAYTHEON COMPANY (US) 2019-02-05 US disclosed
EP-3137438-B1 METHODS TO DESENSITIZE HYDRAZINIUM NITROFORMATE (HNF) RAYTHEON CO (US) 2018-09-12 EP disclosed
EP-3230235-A1 FERROCENYL BONDING AGENT OXIDIZERS Raytheon Company (US) 2017-10-18 EP disclosed
US-6750335-B2 NUCLEOSIDE FOR USE IN THE GENERATION OF PREFERENTIAL OLIGONUCEOTIDES NIGU CHEMIE GMBH (DE) 2004-06-15 US disclosed
WO-2004037807-A2 MEDICINAL ARYLETHANOLAMINE COMPOUNDS GLAXO GROUP LIMITED (GB) 2004-05-06 WO disclosed
EP-1224198-B1 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS NIGU CHEMIE GMBH (DE) 2003-04-23 EP disclosed
US-20020146737-A1 Nucleoside derivatives with photolabile protective groups NIGU CHEMIE GMBH (DE) 2002-10-10 US disclosed
EP-1224198-A1 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS NIGU CHEMIE GMBH (DE) 2002-07-24 EP disclosed
WO-2001032671-A1 NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS NIGU CHEMIE GMBH (DE) 2001-05-10 WO disclosed
EP-1086060-A1 HYDRAZINIUM NITROFORMATE BASED HIGH PERFORMANCE SOLID PROPELLANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 2001-03-28 EP disclosed
WO-1999059940-A1 HYDRAZINIUM NITROFORMATE BASED HIGH PERFORMANCE SOLID PROPELLANTS NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPIJK ONDERZOEK TNO (NL) 1999-11-25 WO disclosed
EP-0959058-A1 Hydrazinium nitroformate based high performance solid propellants NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1999-11-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617738-B2 Removing dissolved gasses from propellant compositions GCN1, CNPY3, GIGYF2 GFER 217/4885RECQL 1111/4885MAOB 4661/4885
US-20020146737-A1 Nucleoside derivatives with photolabile protective groups XRN2, XPA, NSUN2 GFER 4198/4885RECQL 25/4885MAOB 1044/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.