Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1529276 | 0.87 | — | — | |
| Urea SCHEMBL2440792 | 0.85 | ALDH1A1 (0.40) | LMNAMAPTALDH1A1TSHR | |
| SCHEMBL471838 | 0.80 | — | — | |
| SCHEMBL11057434 | 0.79 | — | — | |
| Bicarbonate SCHEMBL15173636 | 0.78 | ALDH1A1 (0.50) | LMNAALOX15ABCC4MAPTHSD17B10 | |
| Bicarbonate SCHEMBL28623469 | 0.77 | LMNA (0.33) | LMNAALOX15ABCC4MAPTHSD17B10 | |
| Bicarbonate SCHEMBL11039726 | 0.77 | ALOX15 (0.46) | LMNAALOX15ABCC4MAPTHSD17B10 | |
| Bicarbonate SCHEMBL1075582 | 0.77 | ALOX15 (0.41) | LMNAALOX15ABCC4MAPTHSD17B10 | |
| SCHEMBL11501255 | 0.73 | — | — | |
| SCHEMBL9335555 | 0.73 | ALDH1A1 (0.53) | LMNAALOX15ABCC4MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2148664-A | — | — | None | — | — | JP | disclosed |
| CN-119183463-A | Curing agent and use thereof | 四国化成工业株式会社 | 2024-12-24 | — | — | CN | disclosed |
| CN-119173501-A | Thiol compound and use thereof | 四国化成工业株式会社 | 2024-12-20 | — | — | CN | disclosed |
| CN-115668571-A | Electrolyte solution, electrochemical device, lithium ion secondary battery, module, and compound | 大金工业株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-115668569-A | Electrolyte solution, electrochemical device, lithium ion secondary battery, and assembly | 大金工业株式会社 | 2023-01-31 | — | — | CN | disclosed |
| CN-110212235-B | Lithium secondary battery electrolyte capable of reducing battery impedance and lithium secondary battery thereof | 广州天赐高新材料股份有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-108349059-A | The system and method that surface processing is carried out to the complex optics blank with functional layer | 依视路国际公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-102484284-A | Nonaqueous electrolyte battery and nonaqueous electrolyte solution | MITSUBISHI CHEM CORP | 2012-05-30 | — | — | CN | disclosed |
| CN-101258022-B | Injection molding method for thin lenses and method for manufacturing laminated photochromic lenses | ESSILOR INT | 2012-02-29 | — | — | CN | disclosed |
| CN-101855590-B | Ophthalmic lens element | VISION CRC LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-101855590-A | Ophthalmic lens element | VISION CRC LTD | 2010-10-06 | — | — | CN | disclosed |
| CN-101258022-A | Injection molding method for thin lenses and method for manufacturing laminated photochromic lenses | ESSILOR INT (FR) | 2008-09-03 | — | — | CN | disclosed |
| EP-0182079-B1 | THERMALLY STABLE ADHESIVE | National Starch and Chemical Investment Holding Corporation (US) | 1992-04-22 | — | — | EP | disclosed |
| JP-H02148664-A | ELECTROLYTE FOR LITHIUM SECONDARY BATTERY | MATSUSHITA ELECTRIC IND CO LTD | 1990-06-07 | — | — | JP | disclosed |
| EP-0244070-A2 | Rapid curing, thermally stable adhesive | National Starch and Chemical Investment Holding Corporation (US) | 1987-11-04 | — | — | EP | disclosed |
| CN-87102640-A | Quick-setting thermally stable adhesive | — | 1987-11-04 | — | — | CN | disclosed |
| US-4692272-A | CROSSLINKING AGENT AND CATALYST | STAUFFER CHEMICAL COMPANY (US) | 1987-09-08 | — | — | US | disclosed |
| US-4652398-A | Rapid curing, thermally stable adhesive composition comprising epoxy resin, polyimide, reactive solvent, and crosslinker | STAUFFER CHEMICAL COMPANY (US) | 1987-03-24 | — | — | US | disclosed |
| US-4604230-A | BLEND OF A POLYIMIDE, TACKIFIER, EPOXY RESIN, HARDENER, CATALYST, AND CROSSLINKING AGENT | STAUFFER CHEMICAL COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0182079-A2 | Thermally stable adhesive | National Starch and Chemical Investment Holding Corporation (US) | 1986-05-28 | — | — | EP | disclosed |