Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614171 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL24408262 | 0.77 | MEN1 (0.41) | MAPTKMT2AMEN1CTSLCTSB | |
| SCHEMBL28310022 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL16285813 | 0.72 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL17730705 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTKMT2A | |
| SCHEMBL14586581 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL8377215 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL8377212 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL19726788 | 0.72 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL24966566 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144839-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | PAHR THERAPEUTICS, INC. | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144839-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | AHR, ARNT, IDO1 | ALDH1A1 316/4885MAPK1 3235/4885L3MBTL1 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.