Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24965965 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDMAPTHSD17B10KMT2A | |
| SCHEMBL17730705 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL21563730 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KMT2AATMTDP1MAPK1 | |
| SCHEMBL28662043 | 0.73 | TDP1 (0.53) | ALDH1A1KMT2AATMTDP1MAPK1 | |
| SCHEMBL28614171 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL6792870 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KMT2AATMTDP1MAPK1 | |
| SCHEMBL6792877 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KMT2AATMTDP1MAPK1 | |
| SCHEMBL4007604 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KMT2AATMTDP1MAPK1 | |
| SCHEMBL20004309 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL24884476 | 0.71 | ATM (0.48) | ALDH1A1HPGDMAPTHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230028336-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | PAHR THERAPEUTICS, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028336-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | AHR, ARNT, IDO1 | ALDH1A1 316/4885HPGD 106/4885MAPT 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.