SCHEMBL24409063

SCHEMBL24409063

O=C(Oc1ccc(O)c(I)c1)OC1C2CC3C1OC(=O)C3C2C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.31
THRA P10827 2/20 0.31
THRB P10828 2/20 0.31
PCNA P12004 2/20 0.31
HIF1A Q16665 2/20 0.31
ALOX5 P09917 1/20 0.31
PTGS2 P35354 1/20 0.31
ABCB11 O95342 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
PGR P06401 1/20 0.31
CHRM2 P08172 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
AR P10275 1/20 0.31
CYP2C9 P11712 1/20 0.31
GABRA1 P14867 1/20 0.31
HPGD P15428 1/20 0.31
RXRA P19793 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24409167 0.86 PTPN2 (0.30)
SCHEMBL24409066 0.85
SCHEMBL24409067 0.82
SCHEMBL24409161 0.77
SCHEMBL24409168 0.77 NR4A1 (0.30)
SCHEMBL24409166 0.73 RXRA (0.33) RXRA
SCHEMBL19678512 0.72
SCHEMBL24409220 0.72
SCHEMBL24409219 0.72 NPC1 (0.33) SMN1; SMN2
SCHEMBL25564584 0.72 LMNA (0.32) POLBLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146931-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146931-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, FGFR1, CLIC1 POLB 985/4885THRA 249/4885THRB 552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.