Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24409197 | 0.89 | POLB (0.45) | SMN1; SMN2MAPK1KDM4EKMT2AALDH1A1 | |
| SCHEMBL24409040 | 0.88 | MAPT (0.49) | SMN1; SMN2MAPK1KDM4EKMT2AALDH1A1 | |
| SCHEMBL24419433 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPK1KDM4EKMT2AALDH1A1 | |
| SCHEMBL24409043 | 0.88 | PTGS2 (0.46) | SMN1; SMN2MAPK1MAPTMMP1MMP9 | |
| SCHEMBL24409308 | 0.87 | PKM (0.56) | SMN1; SMN2KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL24409343 | 0.87 | KDM4E (0.45) | SMN1; SMN2MAPK1KDM4EKMT2AALDH1A1 | |
| SCHEMBL24425293 | 0.87 | ALDH1A1 (0.51) | SMN1; SMN2KDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL24409159 | 0.86 | VEGFA (0.43) | SMN1; SMN2MAPK1KDM4EKMT2AALDH1A1 | |
| SCHEMBL24408953 | 0.86 | TSHR (0.50) | SMN1; SMN2MAPK1KMT2AALDH1A1MAPT | |
| SCHEMBL24419798 | 0.86 | FYN (0.43) | SMN1; SMN2MAPK1KDM4EALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096448-A1 | [(5-PHENYL-5-HETEROARYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | WO | disclosed |
| WO-2022096450-A1 | USE OF [(1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AND THEIR SALTS AND COMPOSITIONS CONTAINING THEM, FOR REDUCING PHYTOTOXIC EFFECTS OF AGROCHEMICALS, IN PARTICULAR OF HERBICIDES, IN USEFUL PLANTS AND CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | WO | disclosed |