SCHEMBL24425293

SCHEMBL24425293

CCOC(=O)COc1cc(-c2ccccc2)n(C)n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
KDM4E B2RXH2 4/20 0.51
MAPT P10636 2/20 0.51
HPGD P15428 2/20 0.51
TP53 P04637 1/20 0.51
HSD17B10 Q99714 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.49
KLK7 P49862 1/20 0.47
SQOR Q9Y6N5 1/20 0.46
PHGDH O43175 1/20 0.46
TSHR P16473 1/20 0.44
HTT P42858 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CASP3 P42574 1/20 0.43
CASP7 P55210 1/20 0.43
CASP9 P55211 1/20 0.43
GAA P10253 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24408948 0.91 KDM4E (0.44) ALDH1A1KDM4EMAPTHPGDTP53
SCHEMBL24408938 0.89 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTHPGDTP53
SCHEMBL24409110 0.89 CXCR1 (0.48) ALDH1A1KDM4EHSD17B10SMN1; SMN2MEN1
SCHEMBL27114062 0.89 TBXAS1 (0.43) ALDH1A1KDM4EMAPTHPGDTP53
SCHEMBL24409325 0.89 KDM4E (0.50) ALDH1A1KDM4EMAPTTP53SMN1; SMN2
SCHEMBL24408995 0.87 ALDH1A1 (0.43) ALDH1A1KDM4EMAPTHPGDTP53
SCHEMBL24409313 0.87 MAPT (0.49) ALDH1A1KDM4EMAPTHPGDTP53
SCHEMBL24419697 0.87 POLB (0.47) ALDH1A1KDM4EMAPTHPGDTP53
SCHEMBL24409332 0.87 SMN1; SMN2 (0.51) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL24409308 0.85 PKM (0.56) ALDH1A1KDM4ESMN1; SMN2TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022096448-A1 [(5-PHENYL-5-HETEROARYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 WO disclosed