Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15936045 | 0.87 | RAB9A (0.55) | SMN1; SMN2KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL6468008 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1HTTHPGD | |
| SCHEMBL27215383 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2AMEN1HTTHPGD | |
| SCHEMBL24414099 | 0.84 | MMP9 (0.73) | MMP9MMP8MMP14NPC1RAB9A | |
| SCHEMBL25410860 | 0.84 | MMP9 (0.73) | MMP9MMP8MMP14NPC1RAB9A | |
| SCHEMBL6163545 | 0.82 | CTSK (0.65) | ACE | |
| SCHEMBL6163542 | 0.82 | CTSK (0.65) | ACE | |
| SCHEMBL3718009 | 0.82 | SMN1; SMN2 (0.52) | MMP8SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL14350869 | 0.82 | MME (0.58) | SMN1; SMN2KMT2AMEN1HTTHPGD | |
| SCHEMBL4332109 | 0.81 | KDM4E (0.53) | MMP8SMN1; SMN2KMT2AALDH1A1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022097540-A1 | PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION | 中外製薬株式会社 | 2022-05-12 | — | — | WO | disclosed |