Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15936045 | 0.83 | RAB9A (0.55) | ALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL12115019 | 0.82 | CTSL (0.51) | KDM4EOPRK1OPRM1OPRD1POLB | |
| SCHEMBL24414243 | 0.81 | MMP9 (0.54) | MMP8ACEALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30511397 | 0.80 | ESRRG (0.43) | KDM4EOPRK1OPRM1OPRD1LTB4R | |
| SCHEMBL7993920 | 0.80 | ALDH1A1 (0.39) | ACEALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL7993921 | 0.80 | ALDH1A1 (0.39) | ACEALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL6468008 | 0.76 | SMN1; SMN2 (0.48) | ALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL27215383 | 0.76 | SMN1; SMN2 (0.48) | ALDH1A1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4324353 | 0.76 | HPGD (0.62) | KDM4EOPRK1OPRM1OPRD1LTB4R | |
| SCHEMBL4319665 | 0.76 | KMT2A (0.64) | KDM4EOPRK1OPRM1OPRD1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | claimed |