Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543074 | 0.95 | PPARG (0.39) | ADRB3PPARGPPARAPPARDADRB2 | |
| SCHEMBL6544135 | 0.85 | ADRB3 (0.56) | ADRB3PPARGPPARAPPARDKDM4E | |
| SCHEMBL6543944 | 0.83 | PPARG (0.54) | ADRB3PPARGPPARAPPARDKDM4E | |
| SCHEMBL1012141 | 0.82 | PPARA (0.40) | ADRB3PPARGPPARAPPARDKDM4E | |
| SCHEMBL6543415 | 0.81 | PPARG (0.42) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL6543126 | 0.81 | PPARA (0.50) | ADRB3PPARGPPARAPPARDKDM4E | |
| SCHEMBL6544050 | 0.80 | PPARG (0.56) | ADRB3PPARGPPARAPPARDKDM4E | |
| SCHEMBL1012350 | 0.79 | MAPT (0.39) | ADRB3PPARGPPARAPPARDKDM4E | |
| SCHEMBL1010511 | 0.79 | HDAC6 (0.43) | PPARGPPARAPPARDKDM4EALDH1A1 | |
| SCHEMBL6543121 | 0.79 | PPARG (0.51) | ADRB3PPARGPPARAPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |