Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543501 | 0.95 | ADRB3 (0.39) | PPARGPPARAPPARDADRB3KCNH2 | |
| SCHEMBL6543921 | 0.84 | MTNR1A (0.43) | PPARGPPARAPPARDMTNR1AMTNR1B | |
| SCHEMBL6544050 | 0.84 | PPARG (0.56) | PPARGPPARAPPARDADRB3KCNH2 | |
| SCHEMBL1010640 | 0.83 | PPARG (0.40) | PPARGPPARAPPARDMTNR1AMTNR1B | |
| SCHEMBL6544135 | 0.82 | ADRB3 (0.56) | PPARGPPARAPPARDADRB3KDM4E | |
| SCHEMBL6543415 | 0.82 | PPARG (0.42) | PPARGPPARAPPARDMTNR1AMTNR1B | |
| SCHEMBL6543944 | 0.80 | PPARG (0.54) | PPARGPPARAPPARDADRB3KCNH2 | |
| SCHEMBL2441903 | 0.80 | PPARG (0.43) | PPARGPPARAPPARDMTNR1AMTNR1B | |
| SCHEMBL1010703 | 0.80 | PPARG (0.39) | PPARGPPARAPPARDADRB3KDM4E | |
| SCHEMBL6543126 | 0.79 | PPARA (0.50) | PPARGPPARAPPARDADRB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |