Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.40 |
| ▸ | ADH1A | P07327 | 1/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629784 | 0.74 | ALDH1A1 (0.45) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL6657229 | 0.73 | KLK1 (0.42) | ADH1BADH1CADH1AADH7ASH1L | |
| SCHEMBL24424686 | 0.68 | ALDH1A1 (0.37) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL8763196 | 0.68 | ADH1B (0.76) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL2198992 | 0.67 | PRSS1 (0.52) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL43651 | 0.67 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL3304771 | 0.66 | ADH1B (0.50) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL9090253 | 0.66 | ARG1 (0.53) | ADH1BADH1CADH1AADH7ALDH1A1 | |
| SCHEMBL24422918 | 0.66 | KMT2A (0.50) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL3320729 | 0.66 | ADH1B (0.46) | ADH1BADH1CADH1AADH7ASH1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |