Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629784 | 0.75 | ALDH1A1 (0.45) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL24423946 | 0.68 | ADH1B (0.40) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL15597736 | 0.66 | PYCR1 (0.47) | ALDH1A1 | |
| SCHEMBL24422918 | 0.64 | KMT2A (0.50) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL8292594 | 0.63 | ALDH1A1 (0.71) | ALDH1A1CDC25BCASP6RCE1KDM4E | |
| SCHEMBL15744180 | 0.62 | KDM4E (0.57) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL20204052 | 0.62 | KEAP1 (0.34) | KDM4EMAPT | |
| SCHEMBL29049154 | 0.62 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHR | |
| SCHEMBL20825948 | 0.62 | PYCR1 (0.51) | ALDH1A1KDM4EGAA | |
| SCHEMBL297623 | 0.62 | ALDH1A1 (0.58) | ALDH1A1CDC25BCASP6RCE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |