SCHEMBL24425333

SCHEMBL24425333

CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 1/20 0.51
▸ CTSB P07858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24690562 1.00 CTSL (0.51) CTSLCTSB
SCHEMBL28732896 1.00 CTSL (0.51) CTSLCTSB
SCHEMBL24583074 0.94 REN (0.47) CTSLCTSB
SCHEMBL30819685 0.93 CTSL (0.46) CTSLCTSB
SCHEMBL19586866 0.91 CTSL (0.54) CTSLCTSB
SCHEMBL19586870 0.91 CTSL (0.54) CTSLCTSB
SCHEMBL19586868 0.91 CTSL (0.54) CTSLCTSB
SCHEMBL24113103 0.91 CTSL (0.42) CTSL
SCHEMBL24020461 0.91 CTSL (0.42) CTSL
SCHEMBL24013950 0.91 CTSL (0.42) CTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122153-A1 Protease Inhibitors as Antivirals ACEA Therapeutics, Inc. (US) 2025-04-17 — — US disclosed
US-11987554-B2 Protease inhibitors as antivirals VIVASOR, INC. (US) 2024-05-21 — — US disclosed
CN-114681443-B Nitrile-containing antiviral compounds 辉瑞大药厂 2024-05-10 — — CN disclosed
EP-4347034-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2024-04-10 — — EP disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 — — US disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 — — US disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 — — US disclosed
CN-116789648-A Nitrile-containing antiviral compounds 辉瑞大药厂 2023-09-22 — — CN disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 — — US disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 — — US disclosed
CN-114466838-B Nitrile-containing antiviral compounds 辉瑞大药厂 2023-05-02 — — CN disclosed
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. 2023-01-26 — — US disclosed
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. 2023-01-26 — — US disclosed
WO-2022256434-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2022-12-08 — — WO disclosed
WO-2022256434-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2022-12-08 — — WO disclosed
US-11452711-B2 Nitrile-containing antiviral compounds PFIZER INC. (US) 2022-09-27 — — US disclosed
CN-114681443-A Nitrile-containing antiviral compounds 辉瑞大药厂 2022-07-01 — — CN disclosed
US-11351149-B2 Nitrile-containing antiviral compounds PFIZER INC. (US) 2022-06-07 — — US disclosed
US-20220142976-A1 Nitrile-Containing Antiviral Compounds PFIZER INC. (US) 2022-05-12 — — US disclosed
CN-114466838-A Nitrile-containing antiviral compounds 辉瑞大药厂 2022-05-10 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122153-A1 Protease Inhibitors as Antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885
US-11452711-B2 Nitrile-containing antiviral compounds ACE2, NOS2, EIF2AK2 CTSL 635/4885CTSB 657/4885
US-20220142976-A1 Nitrile-Containing Antiviral Compounds ACE2, NOS2, EIF2AK2 CTSL 635/4885CTSB 657/4885
US-11753373-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885
US-11987554-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885
US-11351149-B2 Nitrile-containing antiviral compounds ACE2, NOS2, EIF2AK2 CTSL 635/4885CTSB 657/4885
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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