Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP12 | P39900 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18571275 | 0.81 | MMP8 (0.48) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL16924228 | 0.79 | MMP8 (0.50) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL18571476 | 0.78 | MMP8 (0.42) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL2376899 | 0.76 | KMT2A (0.46) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL5696730 | 0.74 | KMT2A (0.45) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL16937291 | 0.74 | KMT2A (0.43) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL2376897 | 0.72 | KMT2A (0.42) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL14426994 | 0.70 | KMT2A (0.41) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL24425828 | 0.68 | MMP8 (0.40) | MMP8MMP12MMP13KMT2AALDH1A1 | |
| SCHEMBL24425807 | 0.66 | PRMT6 (0.52) | KMT2AALDH1A1SMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332443-B2 | Derivatives of halo quinabactin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332443-B2 | Derivatives of halo quinabactin | HDHD5, HSF1, NQO2 | MMP8 4864/4885MMP12 3922/4885MMP13 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.