Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16924229 | 0.83 | PRMT6 (0.46) | PRMT6THRBALDH1A1KDM4EMEN1 | |
| SCHEMBL18571477 | 0.80 | PRMT6 (0.43) | PRMT6THRBALDH1A1KDM4EMEN1 | |
| SCHEMBL19559059 | 0.74 | PRMT6 (0.47) | PRMT6THRBALDH1A1KDM4EMEN1 | |
| SCHEMBL10017405 | 0.71 | PRMT6 (0.65) | PRMT6THRBALDH1A1KDM4EMEN1 | |
| SCHEMBL28408996 | 0.70 | PSIP1 (0.48) | PRMT6THRBALDH1A1KDM4EMAPT | |
| SCHEMBL24425821 | 0.69 | MEN1 (0.44) | ALDH1A1MEN1GAAMAPTHPGD | |
| Dimethylamine SCHEMBL11464572 | 0.67 | PRMT6 (0.59) | PRMT6THRBALDH1A1KDM4EMEN1 | |
| SCHEMBL23665620 | 0.67 | PRMT6 (0.58) | PRMT6THRBALDH1A1KDM4EMEN1 | |
| SCHEMBL24425795 | 0.66 | MMP8 (0.43) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL12630271 | 0.65 | KMT2A (0.47) | PRMT6THRBALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11332443-B2 | Derivatives of halo quinabactin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332443-B2 | Derivatives of halo quinabactin | HDHD5, HSF1, NQO2 | PRMT6 4344/4885THRB 3412/4885ALDH1A1 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.