Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24427943 | 0.82 | ALDH1A1 (0.53) | USP2F2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL24427664 | 0.75 | LMNA (0.43) | USP2F2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL10538281 | 0.75 | ALDH1A1 (0.59) | USP2L3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL24427659 | 0.74 | MAPT (0.37) | USP2F2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15323907 | 0.72 | KMT2A (0.46) | MAPT | |
| SCHEMBL24427221 | 0.72 | HTT (0.45) | ALDH1A1SMN1; SMN2MAPTATMKDM4E | |
| SCHEMBL24307593 | 0.71 | ALOX5 (0.50) | L3MBTL1ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL31693946 | 0.70 | LMNA (0.44) | USP2F2L3MBTL1ALDH1A1MAPT | |
| SCHEMBL9588979 | 0.69 | ALDH1A1 (0.54) | USP2F2L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL627847 | 0.68 | ATM (0.70) | L3MBTL1ALDH1A1SMN1; SMN2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998263-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2022-05-18 | — | — | EP | disclosed |