Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30648924 | 1.00 | MAPT (0.43) | MAPTSLC6A3ALPLALDH1A1SRD5A1 | |
| SCHEMBL19230570 | 0.82 | CYP11B1 (0.45) | MAPTALDH1A1NPC1RAB9AATM | |
| SCHEMBL24380629 | 0.80 | SLC6A3 (0.42) | MAPTSLC6A3ALPLALDH1A1SRD5A1 | |
| SCHEMBL30624594 | 0.79 | MAOA (0.43) | MAPTMEN1KMT2APROKR1CNR1 | |
| SCHEMBL26016719 | 0.78 | SLC6A3 (0.43) | MAPTSLC6A3ALPLALDH1A1SRD5A1 | |
| SCHEMBL23551029 | 0.77 | SLC6A3 (0.42) | MAPTSLC6A3ALPLALDH1A1SRD5A1 | |
| SCHEMBL24428888 | 0.77 | SLC6A3 (0.42) | MAPTSLC6A3ALPLALDH1A1SRD5A1 | |
| SCHEMBL24357704 | 0.77 | ELANE (0.41) | MEN1KMT2APROKR1 | |
| SCHEMBL23195704 | 0.76 | PTGS2 (0.33) | MAPTALDH1A1SRD5A1SRD5A2NPC1 | |
| SCHEMBL29600409 | 0.74 | CA12 (0.41) | MAPTALDH1A1SRD5A1SRD5A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3847157-B1 | PROCESS FOR THE PREPARATION OF METHYL 6-(2,4-DICHLOROPHENYL)-5-[4-[(3S)-1-(3-FLUOROPROPYL)PYRROLIDIN-3-YL]OXYPHENYL]-8,9-DIHYDRO-7H-BENZO[7]ANNULENE-2-CARBOXYLATE AND A SALT THEREOF | SANOFI SA (FR) | 2022-05-18 | — | — | EP | disclosed |