Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | NMT2 | O60551 | 1/20 | 0.53 |
| ▸ | NMT1 | P30419 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22260401 | 0.91 | CASP2 (0.56) | FAAHDNM1CASP2NAAAMETAP2 | |
| SCHEMBL25834507 | 0.91 | CASP2 (0.56) | FAAHDNM1CASP2NAAAMETAP2 | |
| SCHEMBL8847500 | 0.88 | CASP2 (0.59) | CASP2NAAAMETAP2PRCPEPHX1 | |
| SCHEMBL24193475 | 0.88 | CASP2 (0.59) | CASP2NAAAMETAP2PRCPEPHX1 | |
| SCHEMBL8847507 | 0.86 | CASP2 (0.56) | CASP2NAAAMETAP2PRCPEPHX1 | |
| SCHEMBL28340973 | 0.86 | CASP2 (0.61) | FAAHCASP2NAAAMETAP2PRCP | |
| SCHEMBL7286378 | 0.84 | HDAC3 (0.51) | NMT2NMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL3963145 | 0.84 | FAAH (0.58) | FAAHNAAAMETAP2HDAC3HDAC4 | |
| SCHEMBL19957328 | 0.84 | FAAH (0.58) | FAAHNAAAMETAP2HDAC3HDAC4 | |
| SCHEMBL8847821 | 0.84 | ALDH1A1 (0.56) | BCHECASP2NAAAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153722-A1 | CDK2/5 DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153722-A1 | CDK2/5 DEGRADERS AND USES THEREOF | CDK2, CDK5, CDK5R1 | FAAH 3354/4885NMT2 2912/4885NMT1 3678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.