SCHEMBL24429772

SCHEMBL24429772

CCc1ccc(OC)c(S(=O)(=O)N(C)c2noc3ccc(CNC(=O)OC)cc23)c1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ KAT6A Q92794 3/20 0.39
▸ KAT7 O95251 2/20 0.39
▸ KAT6B Q8WYB5 2/20 0.39
▸ KAT5 Q92993 1/20 0.39
▸ KAT8 Q9H7Z6 1/20 0.39
▸ MAPT P10636 4/20 0.38
▸ LMNA P02545 2/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ POLB P06746 2/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ ALPL P05186 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ THRB P10828 1/20 0.36
▸ TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24429774 0.93 KAT7 (0.39) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL28523011 0.82 SMN1; SMN2 (0.38) MAPTLMNAALDH1A1POLBSMN1; SMN2
SCHEMBL21660440 0.82 KAT6A (0.55) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21660434 0.82 MAPT (0.43) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21660565 0.79 KAT7 (0.57) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21641916 0.78 KMT2A (0.39) MAPTLMNAALDH1A1POLBSMN1; SMN2
SCHEMBL21641920 0.77 KMT2A (0.36) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21596801 0.75 KAT6A (0.55) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21660533 0.74 POLB (0.41) KAT6AKAT7KAT6BKAT5KAT8
SCHEMBL21596838 0.72 KAT7 (0.36) KAT6AKAT7KAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT6A 877/4885KAT7 490/4885KAT6B 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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