SCHEMBL21596838

SCHEMBL21596838

CCc1ccc(OC)c(S(=O)(=O)N(OC(=O)C(F)(F)F)c2noc3ccc(CN)cc23)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 3/20 0.36
▸ KAT6A Q92794 3/20 0.36
▸ KAT6B Q8WYB5 2/20 0.36
▸ POLB P06746 2/20 0.35
▸ KAT5 Q92993 1/20 0.34
▸ KAT8 Q9H7Z6 1/20 0.34
▸ MAPT P10636 3/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ TP53 P04637 3/20 0.33
▸ TSHR P16473 1/20 0.33
▸ BRD4 O60885 2/20 0.33
▸ BRD2 P25440 1/20 0.33
▸ BRD3 Q15059 1/20 0.33
▸ ALPL P05186 1/20 0.33
▸ CSNK2A2 P19784 1/20 0.32
▸ CSNK2B P67870 1/20 0.32
▸ CSNK2A1 P68400 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ F2 P00734 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL31605566 0.76 KAT6A (0.54) KAT7KAT6AKAT6BKAT5KAT8
Trifluoroacetic Acid SCHEMBL21596837 0.76 KAT6A (0.54) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21596783 0.75 KAT7 (0.36) KAT7KAT6AKAT6BPOLBKAT5
SCHEMBL30838426 0.75 KAT7 (0.36) KAT7KAT6AKAT6BPOLBKAT5
SCHEMBL24429774 0.72 KAT7 (0.39) KAT7KAT6AKAT6BPOLBKAT5
SCHEMBL24429772 0.72 KAT6A (0.39) KAT7KAT6AKAT6BPOLBKAT5
SCHEMBL21609159 0.72 KAT6A (0.59) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL21660533 0.71 POLB (0.41) KAT7KAT6AKAT6BPOLBKAT5
SCHEMBL21660434 0.69 MAPT (0.43) KAT7KAT6AKAT6BPOLBKAT5
Trifluoroacetic Acid SCHEMBL31605629 0.69 F10 (0.33) POLBSMN1; SMN2KDM4EF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260062393-A1 Compounds CTXT PTY LTD (AU) 2026-03-05 — — US disclosed
US-12365655-B2 Compounds CTXT PTY LTD (AU) 2025-07-22 — — US disclosed
EP-4335439-A2 COMPOUNDS CTXT PTY LTD (AU) 2024-03-13 — — EP disclosed
EP-3810602-B1 COMPOUNDS CTXT PTY LTD (AU) 2023-11-01 — — EP disclosed
US-20220153710-A1 Compounds CTXT PTY LTD (AU) 2022-05-19 — — US disclosed
EP-3810602-A1 COMPOUNDS CTXT Pty Limited (AU) 2021-04-28 — — EP disclosed
CN-112334466-A Compound (I) CTXT私人有限公司 2021-02-05 — — CN disclosed
US-20200039945-A1 Compounds CTXT PTY LIMITED (AU) 2020-02-06 — — US disclosed
WO-2019243491-A1 COMPOUNDS CTXT PTY LIMITED (AU) 2019-12-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220153710-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT7 490/4885KAT6A 877/4885KAT6B 1005/4885
US-20200039945-A1 Compounds SLC10A1, ABCB11, PCSK9 KAT7 490/4885KAT6A 878/4885KAT6B 1007/4885
US-20260062393-A1 Compounds SCN2B, ABCB11, SCN1B KAT7 271/4885KAT6A 160/4885KAT6B 264/4885
US-12365655-B2 Compounds SLC10A1, ABCB11, PCSK9 KAT7 490/4885KAT6A 878/4885KAT6B 1007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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