Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | CDC25C | P30307 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24430013 | 0.92 | MEN1 (0.49) | MEN1KMT2AMGLLHSP90AA1ALDH1A1 | |
| SCHEMBL24430113 | 0.89 | MEN1 (0.54) | MEN1KMT2AMGLLALDH1A1KDM4E | |
| SCHEMBL26205908 | 0.88 | MEN1 (0.48) | MEN1KMT2AFAAHMGLLCDC25A | |
| SCHEMBL24430026 | 0.87 | KMT2A (0.52) | MEN1KMT2AMGLLHSP90AA1ALDH1A1 | |
| SCHEMBL24437318 | 0.87 | RPS6KA3 (0.47) | MEN1KMT2AFAAHMGLLALDH1A1 | |
| SCHEMBL24437423 | 0.86 | MEN1 (0.50) | MEN1KMT2AHSP90AA1ALDH1A1AKR1B1 | |
| SCHEMBL24430114 | 0.85 | MEN1 (0.68) | MEN1KMT2AMGLLALDH1A1KDM4E | |
| SCHEMBL24430074 | 0.85 | MEN1 (0.50) | MEN1KMT2AMGLLALDH1A1KDM4E | |
| SCHEMBL24430002 | 0.83 | MEN1 (0.48) | MEN1KMT2AALDH1A1KDM4ERPS6KA3 | |
| SCHEMBL24430115 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4ERPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339860-A1 | Compounds for the Treatment Of Acute and Chronic Kidney Disease | SOUTHERN RES INST (US) | 2023-10-26 | — | — | US | disclosed |
| US-11753374-B2 | Compounds for the treatment of acute and chronic kidney disease | Southern Reserach Institute (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753374-B2 | Compounds for the treatment of acute and chronic kidney disease | Southern Reserach Institute (US) | 2023-09-12 | — | — | US | disclosed |
| WO-2022109066-A1 | COMPOUNDS FOR THE TREATMENT OF ACUTE AND CHRONIC KIDNEY DISEASE | SOUTHERN RESEARCH INSTITUTE (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022109067-A1 | COMPOUNDS FOR THE TREATMENT OF ACUTE AND CHRONIC KIDNEY DISEASE | SOUTHERN RESEARCH INSTITUTE (US) | 2022-05-27 | — | — | WO | disclosed |
| US-20220153702-A1 | Compounds for the Treatment Of Acute and Chronic Kidney Disease | UAB RESEARCH FOUNDATION | 2022-05-19 | — | — | US | disclosed |
| US-20220153695-A1 | Compounds for the Treatment Of Acute and Chronic Kidney Disease | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153695-A1 | Compounds for the Treatment Of Acute and Chronic Kidney Disease | HMOX1, GLS, HMOX2 | MEN1 4171/4885KMT2A 2088/4885FAAH 537/4885 |
| US-20220153702-A1 | Compounds for the Treatment Of Acute and Chronic Kidney Disease | HMOX1, HMOX2, GLS | MEN1 4651/4885KMT2A 2904/4885FAAH 1800/4885 |
| US-20230339860-A1 | Compounds for the Treatment Of Acute and Chronic Kidney Disease | HMOX1, HMOX2, GLS | MEN1 4651/4885KMT2A 2904/4885FAAH 1800/4885 |
| US-11753374-B2 | Compounds for the treatment of acute and chronic kidney disease | HMOX1, GLS, HMOX2 | MEN1 4171/4885KMT2A 2088/4885FAAH 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.