Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479184 | 0.84 | TSHR (0.46) | POLBENPP3ENPP1ENPP2ALDH1A1 | |
| SCHEMBL7231801 | 0.83 | ALDH1A1 (0.37) | POLBALDH1A1STAT3MEN1KMT2A | |
| SCHEMBL6639675 | 0.81 | MAOA (0.43) | POLBENPP3ENPP1ENPP2STAT3 | |
| SCHEMBL27385149 | 0.79 | ALDH1A1 (0.40) | POLBENPP3ENPP1ENPP2ALDH1A1 | |
| SCHEMBL14368963 | 0.78 | MAOA (0.43) | POLBENPP3ENPP1ENPP2ALDH1A1 | |
| SCHEMBL21987588 | 0.77 | ALDH1A1 (0.38) | POLBENPP3ENPP1ENPP2ALDH1A1 | |
| SCHEMBL12162454 | 0.76 | STAT3 (0.42) | POLBENPP3ENPP1ENPP2ALDH1A1 | |
| SCHEMBL31282646 | 0.76 | KMT2A (0.47) | MEN1KMT2AMMP13 | |
| SCHEMBL25318764 | 0.75 | MAOB (0.45) | ENPP3ENPP1ENPP2ALDH1A1STAT3 | |
| SCHEMBL990946 | 0.75 | DPP4 (0.39) | ENPP3ENPP1ENPP2ALDH1A1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722727-B2 | Antifungal agents | Seynix, Inc. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20110224228-A1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224228-A1 | ANTIFUNGAL AGENTS | GMDS, GBA3, UGGT1 | POLB 3073/4885ENPP3 84/4885ENPP1 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.