Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036538 | 0.78 | CASP3 (0.34) | DPP4ALDH1A1CASP3MEN1KMT2A | |
| SCHEMBL26143890 | 0.76 | MMP13 (0.43) | ALDH1A1STAT3MEN1KMT2ARAB9A | |
| SCHEMBL21987588 | 0.76 | ALDH1A1 (0.38) | ALDH1A1STAT3MEN1KMT2ARAB9A | |
| SCHEMBL2443355 | 0.75 | POLB (0.37) | ALDH1A1STAT3CASP3MEN1KMT2A | |
| SCHEMBL2186144 | 0.74 | GPR119 (0.44) | MEN1KMT2AMMP13CYP2D6GPR119 | |
| SCHEMBL345694 | 0.74 | GPR119 (0.44) | MEN1KMT2AMMP13CYP2D6GPR119 | |
| SCHEMBL345693 | 0.74 | GPR119 (0.44) | MEN1KMT2AMMP13CYP2D6GPR119 | |
| SCHEMBL27385149 | 0.74 | ALDH1A1 (0.40) | ALDH1A1STAT3MEN1KMT2ARAB9A | |
| SCHEMBL30586531 | 0.73 | MMP13 (0.46) | ALDH1A1STAT3MEN1KMT2AMMP13 | |
| SCHEMBL7231801 | 0.73 | ALDH1A1 (0.37) | ALDH1A1STAT3MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011598-A1 | PROCESS FOR PREPARING 4- { (S) -2- (4-(4-CHLOROPHENOXY) PHENOXYMETHYL) PYRROLIDIN-1-YL) } BUTYRIC ACID AND SALTS THEREOF | DECODE GENETICS EHF (IS) | 2011-01-27 | — | — | WO | disclosed |