SCHEMBL24433604

SCHEMBL24433604

CC(C)(C)N(c1ccc(-c2ccccc2)cc1)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
TAAR1 Q96RJ0 3/20 0.40
KIF11 P52732 1/20 0.39
CYP1A2 P05177 2/20 0.39
MAPK1 P28482 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MMP3 P08254 1/20 0.39
BCL2L1 Q07817 1/20 0.39
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36
SLC22A3 O75751 1/20 0.36
SLC6A4 P31645 1/20 0.36
CHKA P35790 1/20 0.35
PTGES O14684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2056786 0.85 MEN1 (0.40) ALDH1A1TAAR1CYP1A2MAPK1CYP3A4
SCHEMBL15447619 0.81 ALDH1A1 (0.43) ALDH1A1TAAR1KIF11CYP1A2MAPK1
SCHEMBL24433605 0.80 MAOA (0.40) ALDH1A1KIF11CYP3A4SMN1; SMN2CHKA
SCHEMBL18372417 0.79 ALDH1A1 (0.41) ALDH1A1TAAR1KIF11CYP1A2MAPK1
SCHEMBL17974865 0.79 ALDH1A1 (0.41) ALDH1A1TAAR1KIF11CYP1A2MAPK1
SCHEMBL2154360 0.79 ALDH1A1 (0.50) ALDH1A1TAAR1KIF11CYP1A2MAPK1
SCHEMBL26002503 0.75 MEN1 (0.38) ALDH1A1CYP1A2MAPK1CYP3A4HSD17B10
SCHEMBL24206102 0.73 KIF11 (0.46) KIF11SMN1; SMN2PTGESALOX5
Biphenyl SCHEMBL27745920 0.73 ALDH1A1 (0.69) ALDH1A1TAAR1KIF11CYP1A2MAPK1
SCHEMBL2778637 0.72 ALDH1A1 (0.61) ALDH1A1TAAR1CYP1A2MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 US disclosed
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-07 US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 US disclosed
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-05-04 US disclosed
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230284516-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, LBR, C1R ALDH1A1 1177/4885TAAR1 181/4885KIF11 4116/4885
US-20230140064-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, CCND3 ALDH1A1 1303/4885TAAR1 1438/4885KIF11 2021/4885
US-20220153769-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ODC1, OCIAD1, OCIAD2 ALDH1A1 102/4885TAAR1 1998/4885KIF11 2107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.