Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9967777 | 1.00 | NPC1 (0.52) | NPC1SMN1; SMN2RAB9ACYP1A2HPGD | |
| SCHEMBL23639908 | 0.79 | NPC1 (0.41) | NPC1SMN1; SMN2RAB9ACYP1A2HPGD | |
| SCHEMBL19538940 | 0.79 | MAPT (0.41) | NPC1SMN1; SMN2RAB9ACYP1A2HPGD | |
| SCHEMBL24434864 | 0.78 | SMN1; SMN2 (0.38) | NPC1SMN1; SMN2RAB9ACYP1A2HPGD | |
| SCHEMBL138489 | 0.76 | MAPT (0.61) | NPC1SMN1; SMN2RAB9ACYP1A2HPGD | |
| SCHEMBL107198 | 0.76 | MAPT (0.61) | NPC1SMN1; SMN2RAB9ACYP1A2HPGD | |
| SCHEMBL24299463 | 0.75 | CYP3A4 (0.37) | SMN1; SMN2CYP1A2KDM4ECYP3A4CYP2D6 | |
| SCHEMBL6299957 | 0.75 | MAPT (0.40) | NPC1SMN1; SMN2RAB9ACYP1A2HPGD | |
| SCHEMBL56244 | 0.75 | MAOB (0.50) | CYP1A2MEN1KMT2ANFE2L2 | |
| SCHEMBL6844031 | 0.75 | MAOB (0.50) | CYP1A2MEN1KMT2ANFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | NPC1 407/4885SMN1; SMN2 4057/4885RAB9A 222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.