SCHEMBL2443502

SCHEMBL2443502

C=CCN1CC(C)N(CC=C)C1=O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
CYP3A4 P08684 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
OPRD1 P41143 1/20 0.32
PRCP P42785 1/20 0.32
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3313650 0.76 CYP3A4 (0.33) CYP3A4
SCHEMBL1830394 0.72 L3MBTL1 (0.38) L3MBTL1
SCHEMBL11207217 0.71
SCHEMBL22700996 0.70 CHRM2 (0.39) MAPTOPRD1PRCP
SCHEMBL14145830 0.69 FAAH (0.31) CYP3A4
SCHEMBL11997297 0.68 CHRM2 (0.46) MAPTCYP3A4L3MBTL1PRCP
SCHEMBL4082877 0.68 CHRM2 (0.46) MAPTCYP3A4L3MBTL1PRCPAR
SCHEMBL4032366 0.68 TP53 (0.33) L3MBTL1
SCHEMBL11238555 0.68 GRM2 (0.48)
SCHEMBL8671581 0.68 L3MBTL1 (0.34) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7206828-A None JP disclosed
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds SHIKOKU CHEMICALS CORPORATION (JP) 2023-11-07 US disclosed
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds SHIKOKU CHEMICALS CORPORATION (JP) 2023-11-07 US disclosed
US-20200369606-A1 THIOL COMPOUNDS, SYNTHESIS METHOD THEREFOR, AND UTILIZATION OF SAID THIOL COMPOUNDS SHIKOKU CHEMICALS CORPORATION (JP) 2020-11-26 US disclosed
EP-2367618-A1 MICROSPHERES Akzo Nobel N.V. (NL) 2011-09-28 EP disclosed
WO-2010072663-A1 MICROSPHERES AKZO NOBEL N.V. (NL) 2010-07-01 WO disclosed
JP-H07206828-A 1,3-DIALKYL-4-METHYL-2-IMIDAZOLIDINONE MITSUI TOATSU CHEM INC 1995-08-08 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369606-A1 THIOL COMPOUNDS, SYNTHESIS METHOD THEREFOR, AND UTILIZATION OF SAID THIOL COMPOUNDS TMT1A, CTH, SLC7A11 MAPT 2185/4885CYP3A4 1859/4885L3MBTL1 2998/4885
US-11807596-B2 Thiol compounds, synthesis method therefor, and utilization of said thiol compounds TMT1A, CTH, SLC7A11 MAPT 2185/4885CYP3A4 1859/4885L3MBTL1 2998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.