Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968351 | 1.00 | CYP3A4 (0.36) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| Benzoic Acid SCHEMBL1068865 | 0.87 | DAO (0.44) | SMN1; SMN2NOS2TSHRALDH1A1MAPT | |
| SCHEMBL29361993 | 0.85 | CYP3A4 (0.41) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL3940465 | 0.85 | CYP3A4 (0.41) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL2857703 | 0.82 | AOC3 (0.41) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL3243887 | 0.81 | ALDH1A1 (0.38) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL10361470 | 0.80 | IDO1 (0.43) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL38652517 | 0.80 | IDO1 (0.43) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL11202355 | 0.79 | ALOX15 (0.36) | CYP3A4ALOX15CASP1CASP7SMN1; SMN2 | |
| SCHEMBL5793872 | 0.79 | CSNK1E (0.45) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904469-B1 | NEW PYROCATECHIN DERIVATIVES | NOVARTIS AG (CH) | 2011-09-21 | — | — | EP | disclosed |
| US-20090143340-A1 | Pyrocatechin Derivatives | SEDELMEIER GOTTFRIED | 2009-06-04 | — | — | US | disclosed |
| EP-1904469-A1 | NEW PYROCATECHIN DERIVATIVES | Novartis AG (CH) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006532-A1 | NEW PYROCATECHIN DERIVATIVES | NOVARTIS AG (CH) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143340-A1 | Pyrocatechin Derivatives | CYP3A43, CYP4B1, CYP4A22 | CYP3A4 8/4885ALOX15 121/4885CASP1 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.