Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | GRB2 | P62993 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018167 | 0.78 | NPC1 (0.47) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20743671 | 0.77 | GABRA1 (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2666361 | 0.77 | S1PR1 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27344405 | 0.77 | GABRA1 (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL27754726 | 0.76 | HSP90AA1 (0.42) | IRAK4GABRA1GABRG2GABRB3GABRA5 | |
| Hydrochloric Acid SCHEMBL11514438 | 0.76 | NPC1 (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29933915 | 0.76 | CYP2A6 (0.62) | MKNK1MKNK2CYP2A6DYRK1A | |
| SCHEMBL4631413 | 0.76 | CYP2A6 (0.62) | MKNK1MKNK2CYP2A6DYRK1A | |
| SCHEMBL20744163 | 0.74 | CYP2A6 (0.54) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30462066 | 0.74 | HSP90AA1 (0.40) | IRAK4CYP2A6ADORA2BDYRK1AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032640-B | Herbicidal compounds | 先正达参股股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-11618743-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2023-04-04 | — | — | US | disclosed |
| US-20220125051-A1 | PRE-HARVEST DESICCATION METHOD | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-28 | — | — | US | disclosed |
| EP-3923727-A1 | PRE-HARVEST DESICCATION METHOD | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| EP-3668855-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-10 | — | — | EP | disclosed |
| CN-113423271-A | Pre-harvest drying method | 先正达农作物保护股份公司 | 2021-09-21 | — | — | CN | disclosed |
| US-20210009561-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-01-14 | — | — | US | disclosed |
| WO-2020164971-A1 | PRE-HARVEST DESICCATION METHOD | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
| EP-3668855-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2020-06-24 | — | — | EP | disclosed |
| CN-111032640-A | Herbicidal compounds | 先正达参股股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| WO-2019034757-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-02-21 | — | — | WO | disclosed |
| WO-2011119518-A1 | SOLUBLE GUANYLATE CYCLASE ACTIVATORS | MERCK SHARP & DOHME CORP. (US) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210009561-A1 | HERBICIDAL COMPOUNDS | DDT, ACHE, GSTO1 | IRAK4 4530/4885GABRA1 969/4885GABRG2 720/4885 |
| US-11618743-B2 | Herbicidal compounds | DDT, ACHE, GSTO1 | IRAK4 4530/4885GABRA1 969/4885GABRG2 720/4885 |
| US-20220125051-A1 | PRE-HARVEST DESICCATION METHOD | GMDS, TREH, DAD1 | IRAK4 4866/4885GABRA1 4264/4885GABRG2 4362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.