Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 4/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806002 | 0.86 | CA1 (0.40) | CA1KDM5AKDM4CSIGMAR1CA12 | |
| SCHEMBL19902989 | 0.84 | KDM5A (0.35) | KDM5AKDM4CALDH1A1LMNATP53 | |
| SCHEMBL5335869 | 0.80 | KDM4C (0.40) | CA1KDM5AKDM4CSIGMAR1CA12 | |
| SCHEMBL14820502 | 0.78 | KDM4C (0.39) | CA1KDM5AKDM4CSIGMAR1CA12 | |
| SCHEMBL19699967 | 0.77 | — | — | |
| SCHEMBL14885533 | 0.75 | ALDH1A1 (0.45) | CA12CA2CA14ALDH1A1LMNA | |
| SCHEMBL23945948 | 0.74 | SIGMAR1 (0.46) | KDM5AKDM4CSIGMAR1CA12CA2 | |
| SCHEMBL19699975 | 0.74 | ALDH1A1 (0.31) | ALDH1A1LMNATP53 | |
| SCHEMBL12927451 | 0.74 | KDM4C (0.42) | CA1KDM5AKDM4CSIGMAR1S1PR2 | |
| SCHEMBL15592245 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022101453-A1 | COMPOUNDS AND METHODS FOR TREATING A CYTOKINE-MEDIATED DISEASE | Conservatoire National des Arts et Métiers (FR) | 2022-05-19 | — | — | WO | disclosed |