Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16532921 | 0.85 | ALDH1A1 (0.37) | ALDH1A1LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL24054682 | 0.84 | LMNA (0.39) | ALDH1A1TSHRLMNA | |
| SCHEMBL19849367 | 0.84 | ALDH1A1 (0.48) | ALDH1A1TSHRLMNAGAAADRB2 | |
| SCHEMBL22329055 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL23419140 | 0.81 | MEN1 (0.47) | ALDH1A1TSHRLMNAHDAC3HDAC4 | |
| SCHEMBL16526493 | 0.81 | LMNA (0.41) | ALDH1A1TSHRLMNAGAACA1 | |
| SCHEMBL19321846 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL10272259 | 0.80 | TSHR (0.54) | ALDH1A1TSHRLMNAHDAC3HDAC4 | |
| SCHEMBL12902809 | 0.79 | CASP2 (0.47) | ALDH1A1TSHRLMNAGAAADRB2 | |
| SCHEMBL13340981 | 0.79 | PAOX (0.37) | ALDH1A1TSHRLMNAGAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347053-B1 | FUNCTIONAL, SEGREGATED, CHARGED TELODENDRIMERS AND NANOCARRIERS AND METHODS OF MAKING AND USING SAME | THE RESEARCH FOUNDATION FOR STATE UNIV OF NEW YORK (US) | 2022-05-25 | — | — | EP | disclosed |