SCHEMBL24445253

SCHEMBL24445253

c1ccc2cc(-n3[nH]c4ccccc43)ccc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3A P46098 2/20 0.43
HTR3E A5X5Y0 1/20 0.43
HTR3B O95264 1/20 0.43
HTR5A P47898 1/20 0.43
HTR3D Q70Z44 1/20 0.43
HTR3C Q8WXA8 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
HSP90AA1 P07900 1/20 0.42
CYP19A1 P11511 1/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
NOTUM Q6P988 1/20 0.37
ALDH1A1 P00352 3/20 0.37
MAPK10 P53779 4/20 0.36
MAPK9 P45984 3/20 0.36
RAB9A P51151 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28345334 0.77 MPI (0.64) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL13711390 0.76 MPI (0.55) ALDH1A1CYP1A2CYP2C9CYP2C19POLB
SCHEMBL19675557 0.73 MPI (0.40) MPI
SCHEMBL274318 0.67 KDM4E (0.56) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL30320243 0.67 KDM4E (0.56) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL23079599 0.67 HTR3A (0.47) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL1114873 0.67 HSP90AA1 (0.46) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL11410044 0.67 TSHR (0.64) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL1562741 0.67 ALDH1A1 (0.59) HTR3AHTR3EHTR3BHTR5AHTR3D
SCHEMBL17533055 0.67 CYP1A2 (0.43) HTR3AHTR3EHTR3BHTR5AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4002509-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2022-05-25 EP disclosed