SCHEMBL24445267

SCHEMBL24445267

C1=CC(c2ccc(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc(-c6ccccc6)cc5)ccc43)cc2)=CCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
TSPO P30536 2/20 0.36
HDAC4 P56524 1/20 0.36
EDNRA P25101 2/20 0.32
EDNRB P24530 1/20 0.32
PTPN1 P18031 2/20 0.32
AKR1C4 P17516 1/20 0.32
AKR1C3 P42330 1/20 0.32
AKR1C2 P52895 1/20 0.32
AKR1C1 Q04828 1/20 0.32
DNM1 Q05193 1/20 0.32
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19387797 1.00 L3MBTL1 (0.41) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL20392242 0.96 L3MBTL1 (0.46) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL22185982 0.95 ATM (0.41) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL29307087 0.95 ATM (0.41) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL19723411 0.94 L3MBTL1 (0.42) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL25490454 0.94 KDM4E (0.34) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL21698273 0.93 L3MBTL1 (0.43) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL21583582 0.92 L3MBTL1 (0.47) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL23352234 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMTSPOHDAC4
SCHEMBL15138429 0.91 TSPO (0.36) L3MBTL1KDM4EATMTSPOHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001287-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2024-01-17 EP disclosed
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
EP-4185086-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-05-24 EP disclosed
EP-4002509-A1 LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME Samsung Electronics Co., Ltd. (KR) 2022-05-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303601-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES MGLL, SELENOI, APOL1 L3MBTL1 68/4885KDM4E 3250/4885ATM 3226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.