Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CD69 | Q07108 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547551 | 0.87 | HTT (0.47) | KMT2AHTTMCL1KDM4EPKM | |
| SCHEMBL8407690 | 0.85 | HTT (0.41) | HTT | |
| SCHEMBL7975719 | 0.84 | FFAR4 (0.41) | HTTMCL1 | |
| SCHEMBL6548447 | 0.84 | L3MBTL1 (0.42) | KMT2ATDP1HTTKDM4ECYP2C19 | |
| SCHEMBL7965637 | 0.83 | PYGL (0.43) | HTTMCL1THRATHRB | |
| SCHEMBL6547683 | 0.81 | HTT (0.40) | HTT | |
| SCHEMBL2442317 | 0.81 | HTT (0.39) | KMT2ATDP1HIF1AHTTKDM4E | |
| SCHEMBL8408794 | 0.81 | HTT (0.39) | KMT2AHTTKDM4EALDH1A1MAPT | |
| SCHEMBL8408754 | 0.81 | HTT (0.39) | KMT2ATDP1HTTKDM4ECYP2C19 | |
| SCHEMBL4479132 | 0.81 | HTT (0.35) | HTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017635-B2 | Phenylalkyl substituted heteroaryl derivatives | FMC CORPORATION (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017635-B2 | Phenylalkyl substituted heteroaryl derivatives | FMC CORPORATION (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017635-B2 | Phenylalkyl substituted heteroaryl derivatives | FMC CORPORATION (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100152045-A1 | Phenylalkyl Substituted Heteroaryl Derivatives | FMC CORPORATION | 2010-06-17 | — | — | US | disclosed |
| US-20100152045-A1 | Phenylalkyl Substituted Heteroaryl Derivatives | FMC CORPORATION | 2010-06-17 | — | — | US | disclosed |
| US-20100152045-A1 | Phenylalkyl Substituted Heteroaryl Derivatives | FMC CORPORATION | 2010-06-17 | — | — | US | disclosed |
| EP-1890694-A1 | PHENYLALKYL SUBSTITUTED HETEROARYL DEVIVATIVES | Bayer CropScience AG (DE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006130403-A1 | PHENYLALKYL SUBSTITUTED HETEROARYL DEVIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152045-A1 | Phenylalkyl Substituted Heteroaryl Derivatives | DDT, CRYAA, CYP19A1 | KMT2A 2846/4885TDP1 1508/4885HIF1A 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.