SCHEMBL6548447

SCHEMBL6548447

O=C(COc1c(Cl)cc(OCC=C(Cl)Cl)cc1Cl)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
KMT2A Q03164 6/20 0.40
MAPT P10636 4/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 4/20 0.40
HTT P42858 3/20 0.39
ALDH1A1 P00352 1/20 0.39
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2444844 0.84 KMT2A (0.50) TDP1KMT2AMAPTSMN1; SMN2HTT
SCHEMBL6548740 0.82 SLC6A4 (0.42) TDP1KMT2AMAPTNPC1RAB9A
SCHEMBL6548269 0.81 LMNA (0.36) KMT2AMAPTHTTLMNA
SCHEMBL8665082 0.81 TDP1 (0.51) TDP1MAPTNPC1RAB9ASMN1; SMN2
SCHEMBL2350339 0.81 TDP1 (0.48) TDP1KMT2AMAPTSMN1; SMN2HTT
SCHEMBL8022439 0.80 PPARA (0.51) L3MBTL1MAPTHTTALDH1A1KDM4E
SCHEMBL6547658 0.80 PPARA (0.48) L3MBTL1MAPTHTTALDH1A1KDM4E
SCHEMBL6547551 0.80 HTT (0.47) L3MBTL1KMT2AMAPTHTTALDH1A1
SCHEMBL6204369 0.79 KMT2A (0.50) L3MBTL1TDP1KMT2AMAPTNPC1
SCHEMBL8075519 0.79 NPC1 (0.49) TDP1KMT2ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975586-B1 OXIME COMPOUNDS, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2004-12-01 EP disclosed
US-6448444-B2 INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-10 US disclosed
US-6437184-B1 INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-08-20 US disclosed
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019569-A1 Oxime compounds, their use, and intermediates for their production CBR3, CBR1, NOX3 L3MBTL1 876/4885TDP1 2528/4885KMT2A 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.