SCHEMBL244489

SCHEMBL244489

[CH2]COc1cc(Br)c(Br)c(Br)c1Br

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
AKR1B1 P15121 5/20 0.40
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALOX15 P16050 1/20 0.32
APEX1 P27695 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11542962 0.81 TDP1 (0.61) TDP1AKR1B1MAPTNPSR1ALOX15
SCHEMBL6046994 0.77 TDP1 (0.56) TDP1AKR1B1MAPTNPSR1
SCHEMBL245322 0.77 TDP1 (0.34) TDP1
SCHEMBL29389799 0.72 TDP1 (1.00) TDP1AKR1B1MAPTNPSR1ALOX15
SCHEMBL943471 0.72 TDP1 (1.00) TDP1AKR1B1MAPTNPSR1ALOX15
SCHEMBL1342629 0.70 AAK1 (0.33) AKR1B1
SCHEMBL7288828 0.69 ALDH1A1 (0.46) TDP1AKR1B1MAPTNPSR1
SCHEMBL4780375 0.69 MAPT (0.64) TDP1AKR1B1MAPTNPSR1
SCHEMBL15169906 0.67 THRB (0.49) TDP1AKR1B1
SCHEMBL148282 0.67 TDP1 (0.39) TDP1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 460 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220040914-A1 FUNCTIONALIZED PRODUCT FABRICATED FROM A RESIN COMPRISING A FUNCTIONAL COMPONENT AND A POLYMERIC RESIN, AND METHOD OF MAKING THE SAME NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2022-02-10 US claimed
CN-111752097-A Self-luminous photosensitive resin composition, color filter and image display device 常州强力电子新材料股份有限公司 2020-10-09 CN claimed
CN-111752098-A Self-luminous photosensitive resin composition, color filter and image display device 常州强力电子新材料股份有限公司 2020-10-09 CN claimed
WO-2020079669-A1 FUNCTIONALIZED PRODUCT FABRICATED FROM A RESIN COMPRISING A FUNCTIONAL COMPONENT AND A POLYMERIC RESIN, AND METHOD OF MAKING THE SAME NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2020-04-23 WO claimed
US-20160122581-A1 POLYMER COMPOSITIONS AND COATINGS FOR FOOD AND BEVERAGE PACKAGING THE COCA-COLA COMPANY (US) 2016-05-05 US claimed
EP-2997094-A1 POLYMER COMPOSITIONS AND COATINGS FOR FOOD AND BEVERAGE PACKAGING The Coca-Cola Company (US) 2016-03-23 EP claimed
WO-2014186285-A1 POLYMER COMPOSITIONS AND COATINGS FOR FOOD AND BEVERAGE PACKAGING THE COCA-COLA COMPANY (US) 2014-11-20 WO claimed
WO-2024125573-A1 PHOTOCURABLE COMPOSITION, AND PHOTOCURABLE COMPOSITION FOR 3D PRINTING AND USE THEREOF 常州强力电子新材料股份有限公司 2024-06-20 WO disclosed
CN-118185278-A Photo-curing composition, 3D printing photo-curing composition and application thereof 常州强力电子新材料股份有限公司 2024-06-14 CN disclosed
WO-2024122572-A1 WAVELENGTH CONVERSION FILM-FORMING COMPOSITION AND FUSED THIOPHENE COMPOUND 日産化学株式会社 2024-06-13 WO disclosed
CN-118027722-A Photocurable coating agent and laminate comprising coating layer using same 爱天思株式会社 2024-05-14 CN disclosed
US-11970596-B2 Photopolymerizable compositions and reaction products thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-04-30 US disclosed
US-20240117103-A1 POLYMER, METHOD OF PREPARING SAME, AND POLYURETHANE PREPARED BY USING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2024-04-11 US disclosed
EP-0848293-A1 Photo-curable resin composition DSM N.V. (NL) 1998-06-17 EP disclosed
EP-0837366-A1 Photocurable resin composition DSM N.V. (NL) 1998-04-22 EP disclosed
EP-0831373-A2 Photo-curable resin compositions and process for preparing a resin-based mold DSM N.V. (NL) 1998-03-25 EP disclosed
EP-0830928-A2 Resin composition and mold made from such resin, for forming fibrous material DSM N.V. (NL) 1998-03-25 EP disclosed
WO-1998001778-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1998-01-15 WO disclosed
WO-1997047671-A1 RADIATION CURABLE RESIN COMPOSITION DSM N.V. (NL) 1997-12-18 WO disclosed
WO-1997038354-A1 PHOTO-CURABLE RESIN COMPOSITION DSM N.V. (NL) 1997-10-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970596-B2 Photopolymerizable compositions and reaction products thereof CBR1, CBR3, POLL TDP1 2191/4885AKR1B1 503/4885MAPT 2605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.