Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779892 | 0.78 | AKR1B1 (0.68) | MAPTNPSR1TDP1POLBL3MBTL1 | |
| SCHEMBL943471 | 0.78 | TDP1 (1.00) | MAPTNPSR1TDP1L3MBTL1ERN1 | |
| SCHEMBL29389799 | 0.78 | TDP1 (1.00) | MAPTNPSR1TDP1L3MBTL1ERN1 | |
| SCHEMBL29878552 | 0.77 | POLB (0.67) | MAPTNPSR1POLBL3MBTL1ERN1 | |
| SCHEMBL298224 | 0.77 | POLB (0.59) | MAPTNPSR1POLBL3MBTL1PRKDC | |
| SCHEMBL369991 | 0.77 | POLB (0.67) | MAPTNPSR1POLBL3MBTL1ERN1 | |
| SCHEMBL28870388 | 0.75 | CA2 (0.67) | MAPTNPSR1POLBL3MBTL1ERN1 | |
| SCHEMBL2388340 | 0.74 | MAPT (0.46) | MAPTNPSR1POLBL3MBTL1ERN1 | |
| SCHEMBL465076 | 0.74 | MAPT (0.46) | MAPTNPSR1TDP1POLBL3MBTL1 | |
| SCHEMBL23900009 | 0.73 | MAPT (0.47) | MAPTNPSR1TDP1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080131420-A1 | METHODS AND COMPOSITIONS FOR TREATING MUCOSAL INFLAMMATION | ACCENTIA, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| WO-2008008494-A2 | METHODS AND COMPOSITIONS FOR TREATING MUCOSAL INFLAMMATION | ACCENTIA BIOPHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
| EP-0744171-B1 | DENTAL COMPOSITION FOR HYPERSENSITIVE DENTIN | SUN MEDICAL CO LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0721773-B1 | Dental composition for relieving dentin hypersensitivity | SUN MEDICAL CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| CN-1060644-C | Dental composition for relieving dentin hypersensitivity | SUN MEDICAL CO LTD (JP) | 2001-01-17 | — | — | CN | disclosed |
| US-5879663-A | Dental composition for dentin hypersensitivity | SUN MEDICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5766328-A | Dental composition for relieving dentin hypersensitivity | SUN MEDICAL CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| EP-0744171-A1 | DENTAL COMPOSITION FOR HYPERSENSITIVE DENTIN | SUN MEDICAL CO., LTD. (JP) | 1996-11-27 | — | — | EP | disclosed |
| CN-1130500-A | Dental composition for relieving dentin hypersensitivity | SUN MEDICAL CO LTD (JP) | 1996-09-11 | — | — | CN | disclosed |
| EP-0721773-A2 | Dental composition for relieving dentin hypersensitivity | SUN MEDICAL CO., LTD. (JP) | 1996-07-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080131420-A1 | METHODS AND COMPOSITIONS FOR TREATING MUCOSAL INFLAMMATION | MMP8, MUC1, MPO | MAPT 4065/4885NPSR1 4308/4885TDP1 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.