Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 18/20 | 0.51 |
| ▸ | THRB | P10828 | 18/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527151 | 0.97 | THRB (0.49) | THRATHRBCYP2C9CYP2C8NPC1 | |
| SCHEMBL29066209 | 0.97 | THRB (0.49) | THRATHRBCYP2C9CYP2C8NPC1 | |
| SCHEMBL24450107 | 0.88 | THRB (0.50) | THRATHRBCYP2C9CYP2C8 | |
| SCHEMBL29066213 | 0.86 | THRB (0.54) | THRATHRBCYP2C9CYP2C8NPC1 | |
| SCHEMBL29526700 | 0.86 | THRB (0.54) | THRATHRBCYP2C9CYP2C8NPC1 | |
| SCHEMBL29527177 | 0.84 | THRA (0.64) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL29527043 | 0.84 | THRA (0.52) | THRATHRBCYP2C9CYP2C8NPC1 | |
| SCHEMBL29066175 | 0.84 | THRA (0.64) | THRATHRBCYP2C9CYP2C8UGT1A1 | |
| SCHEMBL29066258 | 0.84 | THRA (0.52) | THRATHRBCYP2C9CYP2C8NPC1 | |
| SCHEMBL24449975 | 0.83 | THRB (0.52) | THRATHRBCYP2C9CYP2C8UGT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162161-A1 | Novel compounds and their uses as thyroid hormone receptor agonists | THRA, THRB, TSHR | THRA 1/4885THRB 2/4885CYP2C9 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.