SCHEMBL2445101

SCHEMBL2445101

CO[Si](C)(CCCNCc1ccccc1)OC

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.56
CHRM2 P08172 2/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SIGMAR1 Q99720 3/20 0.51
SCN8A Q9UQD0 1/20 0.49
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
DRD4 P21917 1/20 0.45
BCHE P06276 1/20 0.44
MPO P05164 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5160165 0.97 CHRM2 (0.56) MAOACHRM2MEN1KMT2ATDP1
SCHEMBL15361045 0.95 MAOA (0.59) MAOACHRM2MEN1KMT2ATDP1
SCHEMBL15360359 0.90 MEN1 (0.55) MAOACHRM2MEN1KMT2ATDP1
SCHEMBL3921212 0.87 MAOA (0.56) MAOACHRM2MEN1KMT2ATDP1
SCHEMBL48855 0.85 MAOA (0.58) MAOACHRM2MEN1KMT2ATDP1
SCHEMBL12972136 0.84 CHRM2 (0.45) MAOACHRM2TDP1SCN8A
SCHEMBL5160242 0.84 SIGMAR1 (0.56) MEN1KMT2ASIGMAR1GAADRD4
SCHEMBL9066720 0.84 MAOA (0.53) MAOACHRM2MEN1KMT2ATDP1
SCHEMBL25335334 0.83 MAOA (0.56) MAOACHRM2MEN1KMT2ATDP1
Methylamine SCHEMBL3624091 0.82 MAOA (0.55) MAOACHRM2MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3950724-B1 CONJUGATED DIENE COPOLYMER AND METHOD FOR MANUFACTURING CONJUGATED DIENE COPOLYMER ZEON CORP (JP) 2026-02-18 EP disclosed
US-12545691-B2 Tertiary hydroxyl functional alkoxysilanes and methods for preparing thereof HENKEL AG & CO. KGAA (DE) 2026-02-10 US disclosed
US-20250230301-A1 RUBBER COMPOSITION FOR HEAVY-DUTY TIRES ZEON CORPORATION (JP) 2025-07-17 US disclosed
US-20250197612-A1 RUBBER COMPOSITION FOR SIDEWALL ZS ELASTOMERS CO., LTD. (JP) 2025-06-19 US disclosed
US-20250179234-A1 RUBBER COMPOSITION FOR HEAVY-LOAD TIRE ZS ELASTOMERS CO., LTD. (JP) 2025-06-05 US disclosed
EP-3778654-B1 METHOD FOR PRODUCING CONJUGATED DIENE RUBBER ZEON CORP (JP) 2025-02-26 EP disclosed
EP-4502035-A1 RUBBER COMPOSITION FOR HEAVY-DUTY TIRES ZS Elastomers Co., Ltd. (JP) 2025-02-05 EP disclosed
EP-4484488-A1 RUBBER COMPOSITION FOR SIDEWALL ZS Elastomers Co., Ltd. (JP) 2025-01-01 EP disclosed
EP-4484487-A1 RUBBER COMPOSITION FOR HEAVY-LOAD TIRE ZS Elastomers Co., Ltd. (JP) 2025-01-01 EP disclosed
US-12139572-B2 Conjugated diene copolymer and method for manufacturing conjugated diene copolymer ZS ELASTOMERS CO., LTD. (JP) 2024-11-12 US disclosed
WO-2003072628-A1 ENCAPSULATING EPOXY RESIN COMPOSITION, AND ELECTRONIC PARTS DEVICE USING THE SAME HITACHI CHEMICAL CO., LTD. (JP) 2003-09-04 WO disclosed
EP-0844283-B1 Curable resin composition and cured products JSR CORP (JP) 2002-10-09 EP disclosed
US-6313233-B1 CAN BE CURED AND FABRICATED WITHOUT PRODUCING NO CRACKS INTO A CURED PRODUCT SUCH AS A SEMICONDUCTOR DEVICE HAVING A LOW DIELECTRIC CONSTANT, HIGH HEAT RESISTANCE AND MOISTURE RESISTANCE, SUPERIOR ADHESION TO VARIOUS SUBSTRATE MATERIALS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-06 US disclosed
US-20010009936-A1 Method of manufacturing material for forming insulating film JSR CORPORATION (JP) 2001-07-26 US disclosed
EP-1117102-A2 Method of manufacturing material for forming insulating film JSR Corporation (JP) 2001-07-18 EP disclosed
US-6011123-A ORGANOSILANE COMPOUND; POLYAMIC ACIDS HAVING A HYDROLYZABLE SILYL GROUP OR CARBOXYLIC ACID ANHYDRIDE GROUP, OR BOTH, AND POLYIMIDES HAVING A HYDROLYZABLE SILYL GROUP OR CARBOXYLIC ACID ANHYDRIDE GROUP, OR BOTH. JSR CORPORATION (JP) 2000-01-04 US disclosed
EP-0844283-A1 Curable resin composition and cured products JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-27 EP disclosed
EP-0423334-B1 RESIN COMPOSITION AND PROCESS FOR FORMING TRANSPARENT THIN FILM NIPPON KAYAKU KK (JP) 1996-09-18 EP disclosed
US-5180794-A Resin compositions and process for forming transparent thin films NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1993-01-19 US disclosed
EP-0423334-A1 RESIN COMPOSITION AND PROCESS FOR FORMING TRANSPARENT THIN FILM NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545691-B2 Tertiary hydroxyl functional alkoxysilanes and methods for preparing thereof HCCS, EGLN1, RRS1 MAOA 2132/4885CHRM2 1667/4885MEN1 808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.