Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12190422 | 0.86 | CHRM2 (0.50) | CHRM2KDM6BKDM4AKDM2AHRH4 | |
| SCHEMBL2445101 | 0.84 | MAOA (0.56) | CHRM2SCN8ATDP1MAOA | |
| SCHEMBL5160165 | 0.81 | CHRM2 (0.56) | CHRM2SCN8ATDP1MAOA | |
| SCHEMBL2448325 | 0.81 | CHRM2 (0.42) | CHRM2HRH4HRH3SCN8ASMN1; SMN2 | |
| SCHEMBL15361045 | 0.79 | MAOA (0.59) | CHRM2SCN8ATDP1MAOA | |
| SCHEMBL9481297 | 0.75 | CHRM2 (0.51) | CHRM2SCN8AKDM4ETHRBCYP1A2 | |
| SCHEMBL17715564 | 0.74 | HRH4 (0.63) | CHRM2HRH4HRH3SMN1; SMN2CYP1A2 | |
| SCHEMBL8961179 | 0.74 | LOXL2 (0.40) | HRH3CYP1A2LOXL2 | |
| SCHEMBL7871234 | 0.74 | — | — | |
| SCHEMBL12082968 | 0.74 | MC4R (0.58) | CHRM2KDM6BKDM4AKDM2AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100303748-A1 | METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303748-A1 | METHOD FOR LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING A COMPOSITION COMPRISING AN AMINOTRIALKOXY SILANE OR AMINOTRIALKENYLOXY SILANE COMPOUND AND DEVICE | KRT18, FABP4, APMAP | CHRM2 1231/4885KDM6B 1099/4885KDM4A 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.