Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24457585 | 0.74 | LDHA (0.61) | DAOKMOCCR9LDHA | |
| SCHEMBL9497110 | 0.71 | DAO (0.49) | HTR2AHTR2CDAOCYP2A6CYP1A2 | |
| SCHEMBL13677550 | 0.69 | MAPT (0.46) | HTR2AHTR2CCYP2A6CYP1A2MAPT | |
| SCHEMBL8959657 | 0.68 | HTR2C (0.71) | HTR2AHTR2CCYP1A2PRMT5 | |
| SCHEMBL8959650 | 0.68 | HTR2C (0.71) | HTR2AHTR2CCYP1A2PRMT5 | |
| SCHEMBL21391630 | 0.66 | DAO (0.52) | HTR2AHTR2CDAOCYP2A6CYP1A2 | |
| SCHEMBL9494686 | 0.65 | RXFP1 (0.50) | HTR2AHTR2CDAOCYP2A6CYP1A2 | |
| SCHEMBL8959709 | 0.65 | HTR2C (0.71) | HTR2AHTR2CCYP1A2PRMT5 | |
| SCHEMBL8959717 | 0.65 | HTR2C (0.71) | HTR2AHTR2CCYP1A2PRMT5 | |
| SCHEMBL5622574 | 0.64 | FABP4 (0.45) | HTR2AHTR2CCYP2A6CYP1A2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109469-A1 | COMPOUNDS AND METHODS TO TARGET GLUCOSE-STIMULATED PHOSPHOHISTIDINE SIGNALING AND ESOPHAGEAL CANCER GROWTH | HEALTH RESEARCH, INC. (US) | 2022-05-27 | — | — | WO | disclosed |