Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24460151 | 0.83 | GRM5 (0.45) | LMNAHSD17B10RAB9ATSHRKCNMA1 | |
| SCHEMBL16139019 | 0.78 | RAB9A (0.65) | LMNAHSD17B10RAB9ATSHRKCNMA1 | |
| SCHEMBL5728699 | 0.78 | KCNMA1 (0.56) | LMNAHSD17B10RAB9ATSHRKCNMA1 | |
| SCHEMBL9978866 | 0.77 | KCNK3 (0.55) | LMNARAB9ASLC16A3ALDH1A1HPGD | |
| SCHEMBL14363390 | 0.77 | KCNMA1 (0.66) | LMNAHSD17B10RAB9ATSHRKCNMA1 | |
| SCHEMBL14363335 | 0.76 | LMNA (0.58) | LMNAHSD17B10RAB9ATSHRKCNMA1 | |
| SCHEMBL330505 | 0.76 | AR (0.52) | RAB9AGAAHTTKDM4EALDH1A1 | |
| SCHEMBL15552280 | 0.76 | LMNA (0.58) | LMNAHSD17B10RAB9ATSHRGAA | |
| SCHEMBL2022897 | 0.75 | POLB (0.53) | LMNAGAASLC16A3HTTALDH1A1 | |
| SCHEMBL23200284 | 0.74 | LMNA (0.60) | LMNAHSD17B10TSHRGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109148-A1 | SMALL MOLECULE INHIBITORS OF SARS-COV-2 INFECTIONS | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-05-27 | — | — | WO | disclosed |